Long-pulse Nd:YAG treatment increased the dermal collagen level. A substantial increase in the level of procollagens, MMPs, TIMPs, and various growth factors was also observed irrespective of pulse duration, with a trend toward maximal increase at a pulse duration of 12 ms. Long-pulse 1,064-nm Nd:YAG laser irradiation promotes wound-healing process, which is characterized by the induction of growth factor expression and subsequent increase in MMPs and TIMPs, followed by matrix remodeling as confirmed by new procollagen production.
Forty-nine subjects with rosacea enrolled and 12 dropped out. There were no significant differences between LPAN and PDL in the mean reduction of the erythema index (p=0.812; 3.6% vs. 2.8%), improvement of physician's global assessment (p=1.000; 88.9% vs. 89.5%), and subject-rated treatment satisfaction (p=0.842; 77.8% vs. 84.2%). PDL showed more adverse effects including vesicles than LPAN (p=0.046; 26.3% vs. 0.0%). No other serious or permanent adverse events were observed in both treatments. Both LPAN and PDL may be effective and safe treatments for rosacea.
At 8 weeks after the final treatment, all treated nevi showed complete removal of pigmentation, and the mean overall improvement score assessed by physicians, with a quartile grading scale, was 3.6 ± 0.7. The mean number of treatment sessions required to treat CMN (1.5 ± 0.3) was significantly greater than that for junctional (1.1 ± 0.2) or compound (1.2 ± 0.5) AMN. Postinflammatory hyperpigmentation (4.6%), erythema (9.2%), hypertrophic scars (1.5%), and mild atrophic scars (10.8%) were observed, but all resolved within 6 months, except for hypertrophic scars and 1 atrophic scar. Recurrence of pigmentation was observed in 1 CMN (1.5%) during 6 months of follow-up. Combined treatment with Er:YAG laser and long-pulsed alexandrite laser is effective for the removal of small benign melanocytic nevi with minimal adverse effects and low recurrence rates.
Four weeks after the final treatment sessions, the average wrinkle grades of the treated side were reduced by 45.1%. Skin elasticity was significantly increased. The increment of collagen and elastic fiber in papillary dermis was confirmed histologically. No adverse reaction was reported. Pain on the treated side was mild without needing anesthesia. The authors studied new parameters for LPND for improvement of wrinkles and skin laxity with fewer treatment sessions without serious complications. Histologic findings corresponded to clinical improvement. New parameters of LPND can achieve wrinkle improvement with few side effects.
Lutronic’s CLARITY system must be considered among the top laser devices on the market today. In addition to its robust construction and ergonomic design, it offers unparalleled versatility with choice of fluence, pulse width, pulse rate, and spot size for maximum treatment customisation via its industry leading intuitive interface. This provides owners with the ability to safely and successfully treat some of the most commonly seen indications — each a high volume procedure with growth potential worldwide. There is no doubt that CLARITY would be an asset that adds value and utility to any aesthetic practice in the world.
Thirteen patients completed the study. At eight weeks after the final treatment, the decrease in hair counts on the alexandrite laser side (96%) was greater than that on the IPL side (86% vs. pretreatment). The score for patient-evaluated overall satisfaction was higher with the alexandrite laser, although higher pain scores were reported with the alexandrite laser. A burn was observed on one patient on the alexandrite laser side, but was transient and recovered without sequelae. Both systems demonstrated satisfactory hair removal results, as reported by both patients and clinician. The long pulsed alexandrite laser can be used effectively and safely for hair removal in darker skin types.Keywords: Alexandrite laser, Axillary hair removal, Dark skin type, Laser hair removal, Intense pulsed light